Based loosely on the 1988 comedy film, players take control of Beetlejuice (Betelgeuse), who is tasked to scare a family out of their home. Gameplay takes place in two modes: side-scrolling and overhead. In the side-scrolling levels, Beetlejuice has to platform and fend off monstrous insects, toads, octopuses, and more. There are also switches that must be activated and hazards to be avoided.